Both teams are looking to win their first trophy in a generation and have travelled to Prague for the ultimate showdown.
For the Hammers, it could be a crowning night of glory.
David Moyes has broadly done an excellent job since returning to the club in late 2019 and could cap off his best spell in management yet with the first trophy of his career.
Declan Rice, meanwhile, could be going out on a high.
Here’s how to watch the action.
Where to watch Fiorentina vs West Ham
TV channel: In the UK, the final will be broadcast live on BT Sport 1 and BT Sport Ultimate, with coverage getting underway at 6:30pm BST ahead of an 8pm kick-off time.
BT have also announced that the match, along with the Champions League final this weekend, will be made available to watch for free via their website and YouTube channel.
Live stream: A free live stream will be available online via the BT Sport website and YouTube channel.
LIVE coverage: Follow all the action with Standard Sport’s dedicated match blog.