Previously a fixture that has meant so much over the years, there is perhaps not quite as much riding on it these days.
With the Blues having endured nightmare campaign, it is United who are chasing something.
A point at Old Trafford tonight would secure a top four spot for Erik ten Hag’s side and condemn arch rivals Liverpool to the Europa League.
Here’s everything you need to know about the game.
Where to watch Man Utd vs Chelsea
TV channel: The game will be broadcast on Sky Sports Main Event, Sky Sports Premier League and Sky Sports Ultra HDR.
Live stream: The Sky Go website and app will offer subscribers a live stream.
LIVE coverage: Follow all the action with Standard Sport’s dedicated match blog. Nizaar Kinsella will be providing expert analysis.